Loadouts are very subjectively. There are some Cards which are considered better then others but all of them are useful in some regards as the augmentations are only minor changes.
The first thing I look at are the weapons because those make the most difference.
As far as augmentations go there are some which are really good and some which are close to useless.
Good:
-Explodydendron: More blast radius is always good.
-Drilled/Quickdraw: Helps you in fire fights when you run out of ammo.
-Unshakable: Dirty Bomb has a lot of explosions, so if you take less of those that’s an advantage.
-Get Up: You don’t have to charge your defy that much. That gives you more time to focus on other things or allows you to get out of dangerous areas more quickly.
-Extra Supplies: You can use support abilities more often. A huge plus, especially for Sawbonez.
-Double time: Reloading while sprinting is the best.
Bad:
-Pineapple juggler: Only works on Fragger grenades but he can cook those so you wouldn’t have the time to throw them back.
-Tryhard: Most of the time you will not get the health bonus because you will kill at least one person in your life. And if you’re not able to do so that small health boost will not help you.
-Focus: There isn’t really much of a noticeable difference if you have it or not and ADM is mostly useless in the first place.
-Spares: If you are a supporter or have a good one in your team it’s useless.
-Fail safe: Just don’t get hit by your own stuff.
Meh:
-Guardian Angel: Can be useful sometimes but on some maps the beeping will never stop and if you got used to the game you will see the optical effects and don’t need the beep anymore.
-Mechanic: Can be useful but leave the repairing to the specialists, that’s their job.
-Chopper/Quickslash: They ARE good but very situational. If you like going for melee they’re fine. Chapper is good with the Bat or the default knife and quick slash with the Stiletto (The Stiletto insta kills light mercs with the hard attack, so doing it more often is good as it takes some time to hit again. But are there even cards with that combo?)
usw.
But even that list isn’t spot on.
Take proxy’s KE12 Card for example.
Tryhard and Failsafe are pretty bad. But double time and the Hochfir is such a good combo that I consider it the best Proxy card out there.
As you see: 2 Bad + 1 Good = Pure awesomeness
Or Sawbonez’ CR73 is considered the best Sawbonez card. But I prefer the SMG-9 over the Croznitzischitwhatever, Extra supplies over potent packs and the Stiletto over the Bat. So I use the SM72.
Bushwackers BL81 has awesome Augments (Cool, Lockon, Steady) and a nice sidearm but I just hate the Bitchlock so I don’t use it.
TLDR: First look at the weapons and then at the augments and consider what suits you play style the best.
If you go to the store-page you can look up al available cards in the game.
What a textwall… I hope I could help you.